Place the shrimp in a medium mixing bowl and coat with one tablespoon of olive oil, salt, pepper, paprika, garlic powder, onion powder, and cayenne pepper. Use a wooden spoon to toss the shrimp to coat evenly with the oil and spices and set aside.
Melt the butter in a small saucepan over medium-high heat. Add the honey, salt, onion powder, garlic powder, paprika, oregano, thyme, cayenne pepper, and hot sauce and mix with a wooden spoon to combine the ingredients. Remove the cajun honey butter from the heat.
Heat the other tablespoon of olive oil in a medium nonstick skillet over medium-high heat. Add the shrimp and cook for 2-3 minutes until they begin to turn pink. Pour the cajun honey butter over the shrimp and continue to cook for an additional 3-5 minutes until the shrimp are pink and opaque.
Transfer the shrimp to a serving plate and drizzle the sauce from the skillet over the shrimp. Garnish with fresh chopped parsley if desired. Enjoy!